Changing oral vaccine to inactivated polio vaccine might increase mortality

Universal use of inactivated polio vaccine.

OBJECTIVES To present an update on the status of poliomyelitis worldwide, number of cases per year, regions most affected by the disease, vaccines currently available, their risks and benefits, monovalent vaccine use, risks of disseminating a mutant virus in the community, progress that has been made in terms of worldwide eradication and the World Health Organization's (WHO) proposals in this t...

Viral Aetiology of Acute Flaccid Paralysis Surveillance Cases, before and after Vaccine Policy Change from Oral Polio Vaccine to Inactivated Polio Vaccine

Since 1992, surveillance for acute flaccid paralysis (AFP) cases was introduced in Malaysia along with the establishment of the National Poliovirus Laboratory at the Institute for Medical Research. In 2008, the Ministry of Health, Malaysia, approved a vaccine policy change from oral polio vaccine to inactivated polio vaccine (IPV). Eight states started using IPV in the Expanded Immunization Pro...

Monovalent oral polio vaccine: Gates Foundation funds new polio vaccine to accelerate eradication efforts.

Live Oral Poliovirus Vaccine after DPT Polio Vaccine.

In the editorial note on Controlled Drugs which I contributed to the issue of September 9 (Canad. M. A. J., 85: 661, 1961), I find that I have overstated the case for written prescriptions for the amphetamines and the barbiturates. Pharmacists may dispense Controlled Drugs on the strength of a prescription given verbally by a physician as well as by a prescription in writing. The pharmacist mus...

Molecular analyses of oral polio vaccine samples.

It has been suggested that the human immunodeficiency virus (HIV), and thus the acquired immunodeficiency syndrome (AIDS) it causes, was inadvertently introduced to humans by the use of an oral polio vaccine (OPV) during a vaccination campaign launched by the Wistar Institute, Philadelphia, PA, USA, in the Belgian Congo in 1958 and 1959. The "OPV/AIDS hypothesis" suggests that the OPV used in t...